Incidence of altered level of consciousness in hemorrhagic stroke survivors: associated factors from a Korean nationwide study-Reference-Cited by-同舟云学术

Incidence of altered level of consciousness in hemorrhagic stroke survivors: associated factors from a Korean nationwide study

Published:2023-10-26 Issue: Volume: Page:
ISSN:1537-7385
Container-title:American Journal of Physical Medicine & Rehabilitation
language:en
Short-container-title:Am J Phys Med Rehabil

Author:

Ko Nayeon¹,Lee Hyun Haeng¹,Sohn Min Kyun²,Kim Deog Young³,Shin Yong-Il⁴,Oh Gyung-Jae⁵,Lee Yang-Soo⁶,Joo Min Cheol⁷,Lee So Young⁸,Song Min-Keun⁹,Han Junhee¹⁰,Ahn Jeonghoon¹¹,Chang Won Hyuk¹²,Lee Jongmin¹,Kim Yun-Hee

Affiliation:

1. Department of Rehabilitation Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea

2. Department of Rehabilitation Medicine, College of Medicine, Chungnam National University, Daejeon, Republic of Korea

3. Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea

4. Department of Rehabilitation Medicine, Pusan National University School of Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea

5. Department of Preventive Medicine, Wonkwang University, School of Medicine, Iksan, Republic of Korea

6. Department of Rehabilitation Medicine, Kyungpook National University School of Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea

7. Department of Rehabilitation Medicine, Wonkwang University School of Medicine, Iksan, Republic of Korea

8. Department of Rehabilitation Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju City, Republic of Korea

9. Department of Physical and Rehabilitation Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea

10. Department of Statistics, Hallym University, Chuncheon, Republic of Korea

11. Department of Health Convergence, Ewha Womans University, Seoul, Republic of Korea

12. Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

Abstract

Abstract Objective This study aimed to demonstrate the incidence of altered level of consciousness (ALOC) after hemorrhagic stroke and identify factors associated with ALOC at 3 months post-stroke. Design This study used data from a prospective multicenter cohort study conducted in nine hospitals in Korea, and included 1,677 patients with first-ever hemorrhagic stroke. Patients were dichotomized into those with and without ALOC at 3 months post-stroke. Multivariate logistic regression analysis was performed to identify factors associated with subacute to chronic stage ALOC. Results Among patients with hemorrhagic stroke (age: 20–99 years, female 50.21%), the prevalence of ALOC at admission was 38.58% (25.4% [drowsy], 6.38% [stupor], and 6.8% [coma]) and 17.29% 3 months post-stroke. Multivariate logistic regression analysis revealed that independent factors associated with ALOC at 3 months post-stroke included late seizure (odds ratio [95% confidence interval]: 5.93 [1.78–20.00]), stroke progression (3.84 [1.48–9.64]), craniectomy (2.19 [1.19–4.00]), history of complications (1.74 [1.18–2.55]), age at stroke onset (1.08 [1.07–1.10]), and initial GCS score category (0.36 [0.30–0.44]). Conclusion The factors associated with ALOC at 3 months post-stroke should be considered when explaining long-term consciousness status and focused management of modifiable factors in acute care hospitals could help ameliorate ALOC and promote recovery after stroke.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Rehabilitation,Physical Therapy, Sports Therapy and Rehabilitation