Does ozaki procedure have a future as a new surgical approach for aortic valve replacement? a systematic review and meta-analysis

Author:

K. Awad Ahmed12,Farahat Ramadan A.3,Reda Gad Eman4,Shaban Abdelgalil Mahmoud12,Hassaballa Aly Sherif2

Affiliation:

1. Faculty of Medicine

2. Assistant Lecturer of Cardiothoracic Surgery Department, Faculty of Medicine, Ain Shams University

3. Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt

4. Faculty of Medicine, Cairo University, Cairo

Abstract

Background: In 2014, Ozaki et al. introduced the neo-cuspidation (Ozaki procedure), a new valve from the pericardium, to reduce or even prevent the risk of chronic autoimmune inflammation and subsequent rejection or valve degeneration. Thus, the authors aimed to assess the safety and efficacy of the Ozaki technique in treating aortic valve diseases. Materials and methods: A comprehensive search was performed via PubMed, the Cochrane Library, Scopus, and the Web of Science up to 20 February 2022. Random-effects meta-analysis models were employed to estimate the pooled mean and SD or event to the total of the Ozaki procedure. Relevant records were retrieved and analyzed by OpenMeta analyst software. Results: A total of 2863 patients from 21 studies were finally included in our analysis. Ac. Ozaki technique showed statistical significance in terms of mean cardiopulmonary bypass time of 148 mins (95% CI 144–152.2, P<0.001), mean aortic cross-clamp time of 112.46 mins (95% CI 105.116, 119.823, P<0.001), reoperation with a low risk of 0.011 (95% CI 0.005, 0.016, P=0.047), conversion to aortic valve replacement with a low risk of 0.004 (95% CI −0.001, 0.008, P=0.392), finally ICU stay (days) and hospital length of stay (days) with a mean of 2.061 days (95% CI 1.535, 2.587, P<0.001) and 8.159 days (95% CI 7.183–9.855, P<0.001), respectively. Conclusion: The Ozaki procedure provides a safe surgical technique with low mean cardiopulmonary bypass time and aortic cross-clamp time; moreover, a mean of 2-day-postoperative hospital stay was observed with the Ozaki procedure with a low risk of conversion to aortic valve replacement, reoperation, ICU and hospital stay, and death.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine,Surgery

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Prosthetics of heart valves: current trends;Journal of Volgograd State Medical University;2024-08-05

2. Choice of valve substitutes;Indian Journal of Thoracic and Cardiovascular Surgery;2024-04-29

3. The Ross Procedure in a Case of Baraitser-Winter Syndrome: A Case Report;Cureus;2024-01-15

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