1. From the Harvard Medical School, Boston, Massachusetts (D.J.C., D.F., J.L.R., H.J., A.M.B., B.T.H., D.B., G.C.); Departments of Anesthesiology, Perioperative and Pain Medicine (D.J.C., D.F., M.C.F., C.-C. H., A.M.B., G.C.), Medicine (J.L.R., H.J.), Orthopedic Surgery (J.W.), Brigham and Women’s Hospital, Boston, Massachusetts; Department of Neurology, Massachusetts General Hospital, Boston, Massa