Current clinical trials with polo-like kinase 1 inhibitors in solid tumors
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cancer Research,Pharmacology (medical),Pharmacology,Oncology
Reference18 articles.
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3. Small interfering RNA-mediated Polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals.;Guan;Cancer Res,2005
4. Normal cells, but not cancer cells, survive severe Plk1 depletion.;Liu;Mol Cell Biol,2006
5. Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation.;Yim;Mol Cell Biol,2009
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