Electrochemotherapy with bleomycin as an effective local treatment for Kaposi’s sarcoma: a case report

Author:

Niccolò Allievi1,Elena Manzo1,Nadiane Paderno1,Barbara Merelli2,Gianlorenzo Imberti3,Dario Piazzalunga1

Affiliation:

1. Department of Surgery

2. Department of Oncology

3. Department of Dermatology, Papa Giovanni XXIII Hospital, Bergamo, Italy

Abstract

An elderly female patient with a long-standing history of Kaposi’s sarcoma of the lower limbs was referred to the Surgical Department after the subsequential failure of multiple lines of systemic chemotherapy. The patient was also complaining of increasing symptoms including intractable pruritus, which negatively impacted her quality of life. She underwent palliative electrochemotherapy with bleomycin (15 g/m2) on the sarcomatous lesions of the left foot and ankle, which lead to complete clinical response and resolution of symptoms; no adverse events were reported. Electrochemotherapy is a valid option in the palliative treatment of Kaposi’s sarcoma, as it may lead to satisfactory clinical response and symptom control.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cancer Research,Pharmacology (medical),Pharmacology,Oncology

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1. Antineoplastics;Reactions Weekly;2023-11-25

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