1. From the Departments of Biochemistry and Molecular Biology (LNT, RCD, JPV, CBL), Pathology (RG, DF), Urology (RWN) and Physiology and Biophysics (RSR), Dalhousie University, Halifax, Nova Scotia, Canada, Division of Urology (IMT) and Pathology (DAT), Department of Surgery, University of Texas Health Science Center, San Antonio, Texas, and Research and Development, GlaxoSmithKline (RSR), Research Triangle Park, North Carolina