Affiliation:
1. Chaoyang Central Hospital, China Medical University
2. Department of General Surgery, Chaoyang Central Hospital, Chaoyang, Liaoning, China
Abstract
Objective
The objective of this study was to evaluate the safety and effectiveness of radiofrequency ablation (RFA) and transcatheter arterial chemoembolization (TACE) in the treatment of large hepatic hemangiomas (LHH) (5–9.9 cm in diameter).
Methods and materials
This study retrospectively collected data from 82 patients with LHH treated at Chaoyang Central Hospital. The study analyzed the differences in postoperative efficacy, operative time, blood routine, liver and kidney function on the first day after surgery, postoperative hospitalization time and postoperative complications.
Results
There were statistically significant differences in indicators such as white blood cell count, alanine aminotransferase, aspartate aminotransferase and total bilirubin on the first day after surgery between the RFA group (39 cases) and the TACE group (43 cases) (P < 0.001). Compared to RFA, LHH patients treated with TACE had a general complication rate of 39.5% (vs. 43.6%; P = 0.7), a procedure-related complication rate of 30.2% (vs. 59.0%; P = 0.009), an effective rate at 6–12 months postoperatively of 55.8% (vs. 82.1%; P = 0.01), an operating-time of 41.2 ± 14.9 min (vs. 100.8 ± 35.5 min; P < 0.001) and hospitalization costs of 17052.7 ± 1364.8 yuan (vs. 30952.1 ± 4327.6 yuan; P < 0.001).
Conclusion
This study indicates that the efficacy of RFA in treating LHH is significantly superior to TACE. Microwave ablation and RFA appear to be safe treatments for LHH. The TACE group exhibited shorter operating-time, lower hospitalization costs and lower demands on cardiopulmonary function.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Reference35 articles.
1. EASL Clinical Practice Guidelines on the management of benign liver tumours.;J Hepatol,2016
2. Hepatic hemangioma-review.;Bajenaru;J Med Life,2015
3. The evaluation of solitary liver masses.;Bahirwani;Aliment Pharmacol Ther,2008
4. Chinese expert consensus on thermal ablation for hepatic hemangioma(2021 version).;Guo;Chin J Hepatobiliary Surg,2021
5. Radiofrequency ablation for hepatic hemangiomas: a consensus from a Chinese panel of experts.;Gao;World J Gastroenterol,2017