Antibody-suppressing CD8+ T-cell Therapy for Antibody-mediated Rejection: Clinical Considerations
Author:
Affiliation:
1. Department of Surgery, Duke Transplant Center, Duke University School of Medicine, Durham, NC.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Transplantation
Reference9 articles.
1. Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence.;Sellarés;Am J Transplant,2012
2. Alloprimed CD8(+) T cells regulate alloantibody and eliminate alloprimed B cells through perforin- and FasL-dependent mechanisms.;Zimmerer;Am J Transplant,2014
3. Antibody-suppressor CXCR5(+) CD8(+) T cellular therapy ameliorates antibody-mediated rejection following kidney transplant in CCR5 KO mice.;Zimmerer;Am J Transplant,2022
4. Inverse association between the quantity of human peripheral blood CXCR5+IFN-gamma+CD8+ T cells with de novo DSA production in the first year after kidney transplant.;Zimmerer;Transplantation,2020
5. CXCR5+CD8+ T cell–mediated suppression of humoral alloimmunity and AMR in mice is optimized with mTOR and impaired with calcineurin inhibition.;Han;Transplantation,2024
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