Gastric varices

Author:

Wang Thomas J.12,Ryou Marvin12

Affiliation:

1. Brigham and Women's Hospital, Department of Gastroenterology, Hepatology and Endoscopy

2. Harvard Medical School, Boston, Massachusetts, USA

Abstract

Purpose of reviewGastric varices are a rare cause of gastrointestinal bleeding in patients with portal hypertension. There have been significantly advances within endoscopic ultrasound for treatment of gastric varices over the past 5 years in addition to the conventional endoscopic and endovascular therapies. In this review, we will review the latest literature on gastric varices with emphasis on changes to the conventional classification systems and comparisons among the different treatment options for gastric varices in terms of efficacy and safety.Recent findingsThere have been new guidelines proposed by the American Gastrointestinal Association on a simpler classification system compared to the conventional Sarin classification. In addition, endoscopic ultrasound guided coil embolization, a novel treatment pioneered over the past 5 years for gastric varices, has shown increased efficacy and reduced adverse event profile compared to cyanoacrylate glue, the more traditional therapy for gastric variceal bleeding. Options for endovascular therapy overall have not significantly changed over the recent years.SummaryBased on our literature review, we recommend a step-up approach with initial medical and endoscopic management with consideration of endovascular therapies when initial therapies fail.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Gastroenterology

Reference40 articles.

1. A pathophysiologic, gastroenterologic, and radiologic approach to the management of gastric varices;Ryan;Gastroenterology,2004

2. AGA clinical practice update on management of bleeding gastric varices: expert review;Henry;Clin Gastroenterol Hepatol,2021

3. Combination therapy versus monotherapy for EUS-guided management of gastric varices: a systematic review and meta-analysis;McCarty;Endosc Ultrasound,2019

4. Efficacy and safety of endoscopic ultrasound-guided therapy versus direct endoscopic glue injection therapy for gastric varices: systematic review and meta-analysis;Mohan;Endoscopy,2020

5. Comparison of the effects of TIPS versus BRTO on bleeding gastric varices: a meta-analysis;Wang;Can J Gastroenterol Hepatol,2020

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