Surgical Management of Overgrowth Syndrome With Bilateral Vision-Threatening Ptosis

Author:

Linaburg Taylor J.12ORCID,Lahaie-Luna Gabriela12,Pradeep Tejus12,Bhatti Trisha3,Katowitz William12

Affiliation:

1. Division of Ophthalmology, Children’s Hospital of Philadelphia

2. Department of Ophthalmology, University of Pennsylvania

3. Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, U.S.A.

Abstract

We describe the first case reported in ophthalmological literature of the surgical management of a 17-month-old boy with bilateral vision-threatening ptosis, tarsomegaly, ectropion, and euryblepharon secondary to suspected overgrowth syndrome. We elaborate on the major challenges associated with surgical management including the natural and asymmetric growth of oversized tissue, the high likelihood of scarring and formation of disorganized tissue, and risks of frequent intubation in these patients who may have lesions that compromise critical structures such as the airway. Ultimately, surgical intervention is encouraged primarily if vision or ocular health is threatened and secondarily to achieve good cosmesis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference7 articles.

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3. Scarring in patients with PIK3CA-related overgrowth syndromes.;Steiner;JAMA Dermatol,2018

4. A rare case of an asymmetric overgrowth syndrome in a Kenyan African child: a case report and review of literature.;Okello;Cureus,2022

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