1. From the Department of Critical Care Medicine and Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (H.W.); Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada (H.W.); Department of Anesthesiology, Columbia University, New York, New York (H.W., C.G., G.L.); Department of Medicine, Albert Einstein College of Medicine, Montefiore Medica