Longitudinally extensive transverse myelitis, a disabling disorder with a good prognosis: a case series from Nepal

Author:

Dhakal Bishal1,Bogati Kanchan2,Baniya Sunil2,Muhammad Qurat U. A.3,Pathak Bishnu D.4,Pokharel Rojina5,Adhikari Sandip6,Upadhaya Regmi Binit2,Subedi Ram C.7,Pant Prashant8,Paudel Raju9

Affiliation:

1. Bardibas Field Hospital

2. Patan Academy of Health Sciences, Lalitpur

3. Rawalpindi Medical University, Punjab, Pakistan

4. Jibjibe Primary Health Care Center, Rasuwa

5. Manmohan Cardiothoracic and Vascular Transplant Center, Kathmandu

6. Motipur Primary Health Care Center, Rupandehi

7. Grandy International Hospital

8. Star Hospital, Lalitpur, Nepal

9. Shree Birendra Hospital, Nepalese Army Institute of Health Sciences

Abstract

Introduction: Longitudinally extensive transverse myelitis (LETM) is a rare spinal cord disorder with variable etiologies and presentations. It can present solely or as an association with other neurological disorders. Methodology: It was a series of cases of LETM in a tertiary care hospital. Clinical presentation and outcomes: The initial three cases presented with bilateral lower extremity weakness and were diagnosed as transverse myelitis while, the fourth case, already diagnosed as LETM presented with seizure followed by loss of consciousness. All four cases had a good prognosis to date with continued physiotherapy. Conclusion: The early diagnosis of the disease helps to guide the optimal management and decide the potential need for physiotherapy.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine,Surgery

Reference21 articles.

1. Study of clinicoradiological profile and prognosis of longitudinally extensive transverse myelitis from a single tertiary center in Eastern India;Sahoo;Neurol India,2020

2. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders;Wingerchuk;Neurology,2015

3. Longitudinally extensive transverse myelitis: one disease, variable outcomes-a case series;Chandrasekar;J Neurosci Rural Pract,2022

4. Longitudinally extensive transverse myelitis with and without aquaporin 4 antibodies;Kitley;JAMA Neurol,2013

5. Aquaporin 4 IgG serostatus and outcome in recurrent longitudinally extensive transverse myelitis;Jiao;JAMA Neurol,2014

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