The silent threat: investigating the incidence and clinical characteristics of pre-eclampsia and eclampsia in women from tertiary care hospitals of the Democratic Republic of Congo

Author:

Nyakio Olivier12,Cakwira Hugues34,Masimango Gaston24,Kena Louison45,Narayan Gaurang6,Naaz Farheen7,Mugenyi Nathan8,Cyubahiro Vérité K.9,Amani Toussaint45,Balagizi Fabien4,Suvvari Tarun Kumar10,Oduoye Malik Olatunde4,Akilimali Aymar41112

Affiliation:

1. Faculty of Medicine, Evangelic University in Africa

2. Faculty of Medicine, Official University of Bukavu

3. Faculty of Medicine, Catholic University of Bukavu

4. Department of research, Medical Research Circle (MedReC), Bukavu

5. Faculty of Medicine, Université Libre des Pays des Grands Lacs, Goma, DR Congo

6. Department of Obstetrics and Gynecology, Indira Gandhi Government Medical College, Nagpur

7. Medical college, Deccan College of Medical Sciences, Hyderabad

8. Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda

9. Faculty of Medicine, University of Rwanda, Kigali, Rwanda

10. Department of Surgery, Rangaraya Medical College, Kakinada, Andhra Pradesh, India

11. Society for Maternal-Fetal Medicine (SMFM), SW, Washington, DC

12. Department of research, East Africa Medical Students Association, Nairobi, Kenya

Abstract

Background: Pre-eclampsia and eclampsia are medical conditions that can cause severe complications, such as maternal and foetal morbidity and mortality. This study aimed to assess the incidence and characteristics of pre-eclampsia and eclampsia. Methods: From July 2021 to July 2022, the authors conducted a retrospective, cross-sectional, descriptive study in the Department of Obstetrics and Gynaecology of a tertiary care hospital in the Democratic Republic of the Congo (DR Congo). Out of 1236 total deliveries, 40 patients aged 18–35 years with pre-eclampsia and/or eclampsia with complete data in medical records were studied. Results: In the studied group, 3.23% of women (40 cases) experienced pre-eclampsia or eclampsia, with the majority (75%, 30 cases) occurring before childbirth. Among these, 62.5% (25 cases) were first-time mothers. The main complications observed in the mothers included HELLP syndrome and placental abruption, whereas their newborns frequently exhibited delayed in-utero growth. Caesarean delivery was the prevalent birthing method, and the treatments most often used for effective management were magnesium sulfate and nicardipine. Conclusion: The research highlights the common occurrence of eclampsia among patients in the DRC and stresses the critical need for prompt detection of hypertensive complications during pregnancy, aiming to reduce negative health impacts on both mothers and their children.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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