Activation of tuberculosis in recovered COVID-19 patients: a case report

Author:

Al-kayali Rawaa S.1,Kashkash Mohamad F.2,Alhussein Alhajji Azzam H.2ORCID,Khouri Abdullah3

Affiliation:

1. Faculty of Pharmacy, Al-Wataniya Private University, Hama

2. Internal Medicine

3. Thoracic Medicine, Faculty of Medicine, Aleppo University, Aleppo, Syria

Abstract

Introduction and Importance: Currently, coronavirus disease 2019 (COVID-19) and tuberculosis (TB) are among the most important causes of respiratory infections around the world. Both of them are sources of concern for human health and life safety. COVID-19 caused the deaths of millions of people, and many of them suffered from what has become known as ‘post-COVID squeal’. Immunosuppression is one of the most important of these symptoms that leave patients susceptible to severe infections like TB. Case Presentation: In these two cases, the authors observed the development of active TB after a period of COVID recovery. Two patients who were admitted to the hospital complained mainly, among other symptoms, of fever and a continuous cough after a period of COVID-19 recovery. Clinical Discussion: Radiological examination revealed a caving density in the two cases, and the Gene-Xpert test proved the presence of Mycobacterium tuberculosis bacteria despite the negative result of the Ziehl–Neelsen stain. The two patients were improved after standard TB treatment. Conclusion: Patients with post‐COVID‐19 chronic respiratory symptoms should be screened for TB, especially in TB-endemic areas, even though the result of the Ziehl–Neelsen stain was negative.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine,Surgery

Reference15 articles.

1. Latent tuberculosis infection: an overview;Kiazyk;Can Commun Dis Rep,2017

2. Tuberculosis and COVID-19 interaction: a review of biological, clinical and public health effects;Visca;Pulmonology,2021

3. Tuberculosis in times of COVID-19;Zimmer;J Epidemiol Community Health,2022

4. The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines;Agha;Int J Surg,2020

5. Risk factors for latent tuberculosis infection in close contacts of active tuberculosis patients in Aleppo City;Al-Kayali;Eur J Biomed Pharm,2018

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