Early Abortions and Congenital Malformations

Author:

de Fátima Alvim Braga IsabelORCID,Cozendey-Silva Eliana NapoleãoORCID,Ertler Laila ZelkcoviczORCID,dos Santos Martins Thiago GonçalvesORCID,da Silva Santos SabrinaORCID,Silva Bruno de Avilla da Fonseca eORCID,Assumpção Lia RoqueORCID,Waissmann WilliamORCID

Abstract

Introduction Areas with higher agricultural production have higher rates of abortion and malformation, probable related to pesticides. Objective To compare the rates of early abortion and fetal malformation in agricultural and nonagricultural areas. Method A survey was carried out on fetal deaths in children weighing less than 500 g or gestational age less than 22 weeks and fetal malformations in live births. Results From 1996 to 2018, there was an increase in the rates of abortion and, albeit to a lesser extent, malformation. The areas of greater agricultural production have higher rates of fetal mortality and malformation than the others. Conclusions The study suggests that areas with higher use of pesticides have higher rates of abortion and fetal malformations than the others, requiring further observational studies, reducing confounders inherent to the ecological study.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Public Health, Environmental and Occupational Health

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