Affiliation:
1. Department of Dermatology, Henry Ford Health, Detroit, Michigan;
2. College of Human Medicine, Michigan State University, East Lansing, Michigan;
3. Woffles Wu Aesthetic Surgery and Laser Centre, Singapore
Abstract
BACKGROUND
Botulinum toxin A (BoNT-A) treatment has many uses in dermatology. Its mechanism of action and long-term effects for scar formation, rosacea, and antiaging are still being investigated.
OBJECTIVE
To conduct a literature review on BoNT-A to further investigate its use in scar formation, rosacea, and antiaging.
METHODS
A literature review was conducted using PubMed on botulinum toxin treatment for scar formation, rosacea, and antiaging. Studies discussing the toxin mechanism of action and treatment algorithm were included. The authors also provided their personal experience in BoNT-A use for these 3 conditions.
RESULTS
The mechanism of action of Botulinum toxin A in improving scar formation, rosacea, and antiaging is now better understood. While it is effective in the short term, little is still known about how frequently treatment needs to be repeated and if there are any long-term effects.
CONCLUSION
While in vitro studies have supporting evidence on the mechanism of action of BoNT-A on scar formation, rosacea, and antiaging, further studies are needed to identify long-term treatment effects.
Publisher
Ovid Technologies (Wolters Kluwer Health)
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