The Use of a Dehydrated Complete Human Placental Membrane Allograft for Mohs Surgical Defects of the Nose

Abstract

BACKGROUND Repair options for Mohs surgical defects include primary closure, flap or graft, or healing by second intention. These options may not be optimal in all cases. A dehydrated complete human placental membrane (dCHPM) allograft may serve as an alternative repair option. OBJECTIVE To assess the aesthetic and functional outcomes of an alternative repair technique for Mohs surgical defects of the nose. METHODS Twenty patients with Mohs surgical defects of the nose repaired with a dCHPM allograft were retrospectively identified. Photographs were used to demonstrate surgical technique and outcomes. Two blinded observers evaluated final outcomes using the Patient and Observer Scar Assessment Scale. RESULTS Observers rated the scar outcome a combined mean score of 8.4 ± 3.2 (scale 5–50). Patients rated their outcomes a mean of 12.6 ± 7.4 (scale 6–60). The mean “Overall Opinion score” was 2.5 ± 1.8 by patients and 1.9 ± 1.3 by observers (scale 1–10). Limitations This was a single institution study with a small sample size. CONCLUSION Our study demonstrates that dCHPM allografts are a viable alternative repair option for Mohs surgical defects of the nose.