The impact of the COVID-19 pandemic on blood pressure control in patients with treated hypertension-results of the European Society of Hypertension Study (ESH ABPM COVID-19 Study)

Author:

Wojciechowska Wiktoria1,Rajzer Marek1,Kreutz Reinhold2,Weber Thomas3,Bursztyn Michael4,Persu Alexandre5,Stergiou George6,Parati Gianfranco78,Bilo Grzegorz78,Pac Agnieszka9,Grassi Guido10,Mancia Giuseppe7,Januszewicz Andrzej11,

Affiliation:

1. Jagiellonian University Medical College, 1st Department of Cardiology, Interventional Electrocardiology and Arterial Hypertension, Krakow, Poland

2. Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of ClinicalPharmacology and Toxicology, Berlin, Germany

3. Cardiology Department Klinikum Wels-Grieskirchen, Wels, Austria

4. Faculty of Medicine, Hadassah-Hebrew University Jerusalem, Hadassah-Hebrew University Medical Center Mount-Scopus, Jerusalem, Israel

5. Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires Saint-Luc and Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium

6. Hypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital, Athens, Greece

7. Department of Medicine and Surgery, University of Milano-Bicocca

8. Department of Cardiology, S. Luca Hospital, IRCCS, Istituto Auxologico Italiano, Milan, Italy

9. Department of Epidemiology, Chair of Epidemiology and Preventive Medicine, Jagiellonian University Medical College, Krakow, Poland

10. Clinica Medica, Dept of Medicine and Surgery, University of Milano Bicocca, Milan Italy

11. Department of Hypertension, National Institute of Cardiology, Warsaw, Poland

Abstract

Background: We aimed to determine the influence of coronavirus disease 2019 (COVID-19) pandemic on blood pressure (BP) control assessed by ambulatory blood pressure monitoring (ABPM). Methods: Office BP and ABPM data from two visits conducted within a 9–15 months interval were collected from patients treated for hypertension. In the prepandemic group, both visits took place before, while in the pandemic group, Visit-1 was done before and Visit-2 during the pandemic period. Results: Of 1811 collected patients 191 were excluded because they did not meet the required ABPM time frames. Thus, the study comprised 704 patients from the pandemic and 916 from the prepandemic group. Groups did not differ in sex, age, duration of hypertension, frequency of first line antihypertensive drug use and mean 24 h BP on Visit-1. The prevalence of sustained uncontrolled hypertension was similar in both groups. On Visit-2 mean 24 h BP, daytime and nighttime systolic BP and diastolic BP were higher in the pandemic compared to the prepandemic group (P < 0.034). The prevalence of sustained uncontrolled hypertension on Visit-2 was higher in the pandemic than in the prepandemic group [0.29 (95% confidence interval (95% CI): 0.26–0.33) vs. 0.25 (95% CI: 0.22–0.28), P < 0.037]. In multivariable adjusted analyses a significant difference in BP visit-to-visit change was observed, with a more profound decline in BP between visits in the prepandemic group. Conclusions: This study using ABPM indicates a negative impact of the COVID-19 pandemic on BP control. It emphasizes the need of developing strategies to maintain BP control during a pandemic such as the one induced by COVID-19.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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