Lower urinary tract symptoms as an independent predictor of aortic regurgitation in women with cardiac symptoms-Reference-Cited by-同舟云学术

Lower urinary tract symptoms as an independent predictor of aortic regurgitation in women with cardiac symptoms

Published:2023-07 Issue:7 Volume:86 Page:641-645
ISSN:1726-4901
Container-title:Journal of the Chinese Medical Association
language:en
Short-container-title:

Author:

Fan Yu-Hua¹²³,Cheng Wei-Ming²⁴⁵⁶,Huang Yen-Chang⁷

Affiliation:

1. Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC

2. Department of Urology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC

3. Shu-Tien Urological Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC

4. Program in Molecular Medicine, School of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC

5. Institute of Biopharmaceutical Science, School of Life Science, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC

6. Division of Urology, Department of Surgery, Taipei City Hospital, Zhongxiao Branch, Taipei, Taiwan, ROC

7. Division of Cardiology, Department of Medicine, Taipei City Hospital, Taipei, Taiwan, ROC

Abstract

Background: Very few studies have focused on the correlation between structural heart disease and lower urinary tract symptoms. In this study, we applied echocardiography to explore the correlation between lower urinary tract symptoms and structural heart disease. Methods: In this single-center, prospective, cross-sectional study, we enrolled adult women undergoing echocardiography for suspected cardiac abnormalities causing cardiac symptoms between February 1, 2021, and March 31, 2021. All participants completed a questionnaire regarding demographic information and lower urinary tract symptoms, which were assessed according to the International Prostate Symptom Score. Results: A total of 165 women aged 69.96 ± 10.20 years were enrolled. The prevalence of moderate-to-severe aortic regurgitation in patients with moderate-to-severe lower urinary tract symptoms was significantly higher than that in patients with mild lower urinary tract symptoms (33.3% vs 13.6%, p = 0.008). The prevalence of other echocardiographic abnormalities was not associated with severity of lower urinary tract symptoms. Multivariable logistic regression analyses revealed that moderate-to-severe lower urinary tract symptoms predicted moderate-to-severe aortic regurgitation (p = 0.007; odds ratio: 3.560; 95% confidence interval: 1.409-8.993). Furthermore, the International Prostate Symptom Score storage subscore (p = 0.001; odds ratio: 1.285; 95% confidence interval: 1.111–1.486), except the voiding subscore, was an independent predictor of moderate-to-severe aortic regurgitation. Conclusion: Moderate-to-severe lower urinary tract symptoms, especially storage symptoms, are an independent predictor of the co-existence of moderate-to-severe aortic regurgitation in women with cardiac symptoms. Early cardiological referral of patients with moderate-to-severe lower urinary tract symptoms and cardiac symptoms may improve their general health.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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