Radiation issue in clinical nuclear molecular imaging

Author:

Chiu Chuang-Hsin1,Yeh Skye Hsin-Hsien2,Chen Ming-Rong3,Peng Nan-Jing4,Huang Wen-Sheng145

Affiliation:

1. Department of Nuclear Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

2. School of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC

3. Department of Pharmacy, Cheng-Hsin General Hospital, Taipei, Taiwan, ROC

4. Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC

5. Department of Nuclear Medicine, Cheng-Hsin General Hospital, Taipei, Taiwan, ROC

Abstract

Radiation is ubiquitous in nature, and radiation is also widely used in various fields of medicine, agriculture, and industry. Current biological doses below 100 mSv are called low-dose radiation (LDR). Scientists have no consensus of effects on humans below this dose, so a variety of dose-response curve theories have been derived. This approach makes the public believe that even a small dose of radiation has adverse side effects, and overreact to refuse the related medical procedures for fear of radiation. The linear non-threshold (LNT) model has been used in radiation protection for over 40 years however, adverse effects from low dose, low-dose rate (LDDR) exposures are not detectable. Nuclear molecular imaging is LDR, using different radionuclides or combining with specific ligands (carries) to form “radiopharmaceuticals” for functional or pathological evaluations of diseases. As an integral part of patient care, nuclear medicine is used in the diagnosis, management, treatment, follow-up, and prevention of diseases. Therefore, this paper discusses literature review and provides appropriate scientific data and communication to help the peers and the public understand its advantage and disadvantage.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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