Pharmacogenetics of Anesthetic and Analgesic Agents

Author:

Palmer Stephen N.1,Giesecke N Martin2,Body Simon C.2,Shernan Stanton K.2,Fox Amanda A.3,Collard Charles D.4,Warltier David C.

Affiliation:

1. Scientific Medical Writer.

2. Assistant Professor of Anesthesia.

3. Instructor of Anesthesia.

4. Associate Professor of Anesthesia.

Abstract

Predicting a patient's response to a particular drug has long been a goal of clinicians. Rapid advances in molecular biology have enabled researchers to identify associations between an individual's genetic profile and drug response. Pharmacogenetics is the study of the molecular mechanisms that underlie individual differences in drug metabolism, efficacy, and side effects. The pharmacogenetics of commonly used anesthetic and analgesic agents are reviewed.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Anesthesiology and Pain Medicine

Reference77 articles.

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