Author:
Gepts Elisabeth,Shafer Steven L.,Camu Frederic,Stanski Donald R.,Woestenborghs Robert,Van Peer Achiel,Heykants Jos J.P.
Abstract
Abstract
Background
The pharmacokinetic profiles of sufentanil available in the literature are conflicting because of methodologic differences. Length of sampling and assay sensitivity are key factors involved in accurately estimating the volumes of distribution, clearances, and elimination phase. The unit disposition function of increasing doses of sufentanil were investigated and the influence of dose administered on the linearity of pharmacokinetics was assessed.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Anesthesiology and Pain Medicine
Cited by
162 articles.
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