CYCLOSPORINE INHIBITION OF LEUKOCYTE CALCINEURIN IS MUCH LESS IN WHOLE BLOOD THAN IN CULTURE MEDIUM
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Transplantation
Reference15 articles.
1. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity
2. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
3. Calcineurin acts in synergy with PMA to inactivate I kappa B/MAD3, an inhibitor of NF-kappa B.
4. Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.
5. Calcineurin Activates Transcription from the GM-CSF Promoter in Synergy with Either Protein Kinase C or NF-κB/AP-1 in T-Cells
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