EX VIVO ADENOVIRUS-MEDIATED GENE DELIVERY LEADS TO LONG-TERM EXPRESSION IN PANCREATIC ISLET TRANSPLANTS1
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Transplantation
Reference15 articles.
1. Transfer of Genes to Humans: Early Lessons and Obstacles to Success
2. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
3. MHC class I-cestricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
4. Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels.
5. Efficient Gene Transfer To Pancreatic Islets Mediated By Adenoviral Vectors
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1. Synergism of highly transducible adenovirus encoding heme oxygenase 1 gene and low-dose immunosuppressants for successful outcomes of xenotransplanted pancreatic islet;Journal of Industrial and Engineering Chemistry;2017-03
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3. Immunity to islet grafts transduced with adenovirus vectors does not inhibit long-term islet function;Transplant Immunology;2009-05
4. Adenoviral overproduction of interleukin-1 receptor antagonist increases beta cell replication and mass in syngeneically transplanted islets, and improves metabolic outcome;Diabetologia;2007-01-13
5. Biological and Biomaterial Approaches for Improved Islet Transplantation;Pharmacological Reviews;2006-05-19
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