Favorable tumor uptake and nuclear transport of Auger electrons by nuclear targeting with 111In-trastuzumab in an intraperitoneal tumor mouse model

Author:

Keiko Li Huizi,Hasegawa Sumitaka

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

Reference9 articles.

1. Radiobiologic principles in radionuclide therapy.;Kassis;J Nucl Med,2005

2. Exploiting active nuclear import for efficient delivery of Auger electron emitters into the cell nucleus.;Rosenkranz;Int J Radiat Biol,2020

3. Peptide motifs for insertion of radiolabeled biomolecules into cells and routing to the nucleus for cancer imaging or radiotherapeutic applications.;Costantini;Cancer Biother Radiopharm,2008

4. Transcriptomic signatures of Auger electron radioimmunotherapy using nuclear targeting (111)In-Trastuzumab for potential combination therapies.;Li;Cancer Biother Radiopharm,2015

5. Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid leukemia cells.;Chen;J Nucl Med,2006

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