Cutaneous Metastasis of Alveolar Rhabdomyosarcoma in a Child

Author:

Nör Felipe12,Castro Juan Pablo2,Wongpattaraworakul Wattawan2,Buatti John M.3,Gordon David4,Powers Jennifer G.5,Terry William4,Hellstein John2,Tanas Munir6,Stone Mary7

Affiliation:

1. Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI;

2. Department of Oral Pathology, Radiology and Medicine, University of Iowa College of Dentistry, Iowa City, IA;

3. Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA;

4. Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA;

5. Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, IA;

6. Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA; and

7. Department of Dermatopathology, University of Iowa Hospitals and Clinics, Iowa City, IA.

Abstract

Abstract: Rhabdomyosarcoma (RMS) is one of the most common soft tissue sarcomas in children. This lesion is classically included in the generic group of “small round blue cell tumors” along with other entities that share similar microscopic features. Although the head and neck region is a frequent site for primary tumors, cutaneous metastases of RMS involving this anatomical location are rare in the pediatric population. We report a case of a 12-year old girl previously diagnosed with a primary alveolar RMS involving the left maxillary sinus, presenting with a metastatic lesion on the skin of the left temple area. Along with a brief review of the previous case reports on the topic, we highlight the initial immunohistochemistry panel useful for diagnosing this tumor.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Dermatology,General Medicine,Pathology and Forensic Medicine

Reference25 articles.

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4. Rhabdomyosarcoma of the head and neck in children;Hicks;Oral Oncol.,2002

5. Clinicopathologic traits and prognostic factors associated with pediatric sinonasal rhabdomyosarcoma;Siddiqui;Int Forum Allergy Rhinol.,2019

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