Nail as a Window to Diagnosing Multisystem Langerhans Cell Histiocytosis: A Case Report and Review of Literature

Author:

Somasundaram Arun1ORCID,Periyasamy Senthil Kumar1,Arunachalam Narayanan1,Suyamprakasam Vimala Tirekha1,Jinkala Sree Rekha2,Dhandapany Gunasekaran3,Sivaranjini Ramassamy1ORCID

Affiliation:

1. Department of Dermatology, JIPMER, Puducherry, India;

2. Department of Pathology, JIPMER, Puducherry, India; and

3. Department of Pediatrics, JIPMER, Puducherry, India.

Abstract

Abstract: Nail involvement in Langerhans cell histiocytosis is rarely reported in the literature. According to the reported cases, it is believed that the involvement of nails has a poor prognosis because of multisystem involvement. Performing a nail bed biopsy might be challenging for children. We report a child in whom nail bed biopsy served as the sole clue to the diagnosis of Langerhans cell histiocytosis in absentia of skin clue on a background of advanced multisystem involvement.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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