Pathophysiological Hypothesis of COVID-19 Psychosis

Author:

Lisi Gisela Roxana Edith1,Appiani Francisco1,Basile María Eugenia2,Garro Marcelo1,Duarte Juan Manuel1

Affiliation:

1. Neuropsychopharmacology Unit, Dirección de Docencia e Investigación

2. Mental Health Unit, Hospital de Clínicas “José de San Martín,” Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.

Abstract

Abstract In December 2019, a new coronavirus called SARS-CoV-2 was discovered in patients with pneumonia of unknown cause. Although respiratory symptoms mainly characterize infection by this virus, neuropsychiatric manifestations of the disease are becoming more and more frequent. Among them, the appearance of psychotic outbreaks in patients experiencing the infection or after a short time after it has resolved is remarkable. This narrative review aims to describe the possible relationship between SARS-CoV-2 and the onset of psychosis by developing the neurotropic capacities of the virus and analyzing the neurobiology of psychoses.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Psychiatry and Mental health

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