Successful Treatment of Both Refractory Neuroleptic Malignant Syndrome and Subsequent Catatonia With Electroconvulsive Therapy in a Patient With Suspected Kufs Disease-Reference-Cited by-同舟云学术

Successful Treatment of Both Refractory Neuroleptic Malignant Syndrome and Subsequent Catatonia With Electroconvulsive Therapy in a Patient With Suspected Kufs Disease

Published:2024-06-03 Issue: Volume: Page:
ISSN:1533-4112
Container-title:The Journal of ECT
language:en
Short-container-title:J ECT

Author:

Celik Sacha¹^ORCID,de Gennaro Veronica¹,C.-P.-Silva João¹^ORCID,Swierkosz-Lenart Kevin²,von Gunten Armin²

Affiliation:

1. Old Age Psychiatry Clinic, Department of Psychiatry, Hôpital du Valais, Sion, Switzerland

2. Old Age Psychiatry Service, Department of Psychiatry, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.

Abstract

Abstract We describe a patient suffering from probable Kufs disease who developed a neuroleptic malignant syndrome (NMS) after use of an antipsychotic agent over some weeks during hospitalization due to neuropsychiatric symptoms. Transferred to the neurology department, the patient quickly developed catatonic features. She did not respond to usual medical treatment but did respond to electroconvulsive therapy (ECT). The patient worsened following a nosocomial SARS-CoV-2 infection but improved again during a second course of ECT. We discuss Kufs disease as a potential risk factor for NMS and address the link between NMS and catatonia as well as the indication for ECT in both disorders. We also discuss the impact of SARS-CoV-2 infection on the clinical outcome. We describe the long recovery process and the secondary worsening of the patient on a cognitive level.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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