SLN124, a GalNAc-siRNA Conjugate Targeting TMPRSS6, Efficiently Prevents Iron Overload in Hereditary Haemochromatosis Type 1-Reference-Cited by-同舟云学术

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SLN124, a GalNAc-siRNA Conjugate Targeting TMPRSS6, Efficiently Prevents Iron Overload in Hereditary Haemochromatosis Type 1

Published:2019-10-23 Issue:6 Volume:3 Page:e301
ISSN:2572-9241
Container-title:HemaSphere
language:en
Short-container-title:

Author:

Altamura Sandro,Schaeper Ute,Dames Sibylle,Löffler Kathrin,Eisermann Mona,Frauendorf Christian,Müdder Katja,Neves Joana,Muckenthaler Martina U.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Hematology

Reference15 articles.

1. Hereditary hemochromatosis;Pietrangelo;Ann Rev Nutr.,2006

2. Haemochromatosis;Brissot;Nat Rev Dis Primers.,2018

3. Hereditary hemochromatosis: patient experiences of the disease and phlebotomy treatment;Brissot;Transfusion.,2011

4. Hepcidin and the BMP-SMAD pathway: an unexpected liaison;Silvestri;Vitam Horm.,2019

5. HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression;Wu;Blood.,2014

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1. The oral ferroportin inhibitor vamifeport prevents liver iron overload in a mouse model of hemochromatosis;HemaSphere;2024-09

2. Skin complications during iron chelation therapy for beta-thalassemia: overview and treatment approach;International Journal of Hematology;2024-08-01

3. Disease burden, management strategies, and unmet needs in α‐thalassemia due to hemoglobin H disease;American Journal of Hematology;2024-07-22

4. Rational In Silico Design of Selective TMPRSS6 Peptidomimetic Inhibitors via Exploitation of the S2 Subpocket;Journal of Medicinal Chemistry;2024-07-19

5. SLN124, a GalNAc conjugated 19‐mer siRNA targeting tmprss6, reduces plasma iron and increases hepcidin levels of healthy volunteers;American Journal of Hematology;2023-07-27

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