JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Hematology
Reference15 articles.
1. Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia;Vicente;Haematologica.,2015
2. The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia;Liu;Nat Genet.,2017
3. JAK/STAT signaling in hematological malignancies;Vainchenker;Oncogene.,2012
4. Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia;Kontro;Leukemia.,2014
5. The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acutelymphoblastic leukemia and confers a higher risk of relapse;Bandapalli;Haematologica.,2014
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