Limited Sampling Strategy of Partial Area Under the Concentration–Time Curves to Estimate Midazolam Systemic Clearance for Cytochrome P450 3A Phenotyping

Author:

Masters Joanna C.,Harano Denise M.,Greenberg Howard E.,Tsunoda Shirley M.,Jang In-Jin,Ma Joseph D.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Pharmacology (medical),Pharmacology

Reference38 articles.

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2. . The conduct of in vitro and in vivo drug-drug interaction studies: a PhRMA perspective.;Bjornsson;J Clin Pharmacol,2003

3. Cytochrome P-450 3A4: regulation and role in drug metabolism.;Guengerich;Annu Rev Pharmacol Toxicol,1999

4. . Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.;Tsunoda;Clin Pharmacol Ther,1999

5. . Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.;Thummel;J Pharmacol Exp Ther,1994

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