Impact of Age and Genotype on Serum Concentrations of Valproic Acid and Its Hepatotoxic Metabolites in Chinese Pediatric Patients With Epilepsy
Author:
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Pharmacology (medical),Pharmacology
Reference23 articles.
1. Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy;Löscher;CNS Drugs.,2002
2. The role of pharmacogenetics in the metabolism of antiepileptic drugs: pharmacokinetic and therapeutic implications;Klotz;Clin Pharmacokinet.,2007
3. Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review;Silva;J Inherit Metab Dis.,2008
4. Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes;Surendradoss;Toxicol Appl Pharmacol.,2012
5. Valproic acid I: time course of lipid peroxidation biomarkers, liver toxicity, and valproic acid metabolite levels in rats;Tong;Toxicol Sci.,2005
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3. Successful LC-MS/MS assay development and validation for determination of valproic acid and its metabolites supporting proactive pharmacovigilance;Journal of Pharmaceutical and Biomedical Analysis;2023-09
4. Effects of UGT1A, CYP2C9/19 and ABAT polymorphisms on plasma concentration of valproic acid in Chinese epilepsy patients;Pharmacogenomics;2023-02
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