Impact of CYP2D6, CYP3A5, and ABCB1 Polymorphisms on Plasma Concentrations of Donepezil and its Metabolite in Patients with Alzheimer’s Disease

Author:

Kagawa Yoshiyuki,Yamamoto Yoshiaki,Ueno Ayami,Maeda Toshio,Obi Tomokazu

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Pharmacology (medical),Pharmacology

Reference27 articles.

1. 2016 Alzheimer's disease facts and figures;Alzheimers Dement.,2016

2. Donepezil use in Alzheimer disease;Barner;Ann Pharmacother.,1998

3. Donepezil plasma concentrations, CYP2D6 and CYP3A4 phenotypes, and cognitive outcome in Alzheimer's disease;Coin;Eur J Clin Pharmacol.,2016

4. Absorption, distribution, metabolism, and excretion of donepezil (aricept) after a single oral administration to rat;Matsui;Drug Metab Dispos.,1999

5. Do CYP3A and ABCB1 genotypes influence the plasma concentration and clinical outcome of donepezil treatment?;Magliulo;Eur J Clin Pharmacol.,2011

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