Use of Age-Adjusted Serum Creatinine in a Vancomycin Pharmacokinetic Model Decreases Predictive Performance in Elderly Patients

Author:

Tong Dominic M. H.,Hughes Jasmine H.,Keizer Ron J.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Pharmacology (medical),Pharmacology

Reference5 articles.

1. Prospective validation of a model‐informed precision dosing tool for vancomycin in intensive care patients;ter Heine;Br J Clin Pharmacol.,2020

2. Methodological study of vancomycin dosing in elderly patients using actual serum creatinine versus rounded serum creatinine;Young;Drugs R D.,2017

3. Hospitalized patients with and without hemodialysis have markedly different vancomycin pharmacokinetics: a population pharmacokinetic model-based analysis [published correction appears in Ther Drug Monit. 2019 Aug;41(4):549];Goti;Ther Drug Monit.,2018

4. Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting;Broeker;Clin Microbiol Infect.,2019

5. Towards precision dosing of vancomycin in critically ill patients: an evaluation of the predictive performance of pharmacometric models in ICU patients [published online ahead of print, 2020 Jul 13];Cunio;Clin Microbiol Infect.,2020

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