Renal cell carcinoma: an overview of the epidemiology, presentation, histopathological characteristics, and surgical treatment variation between old and new era – a cross-sectional study

Abstract

Introduction: The landscape of renal cell carcinoma (RCC) diagnosis, staging, and treatment has evolved over the last decades. Our study to report our experience in this evolution over a 30-years’ time. Methodology: A database of patients who underwent nephrectomy for RCC was collected and compared between new era (2017–2021) and old era (1992–2001). Results: One hundred thirty-six patients collected in new era compared to 132 in old era, results showed that more patients diagnosed at earlier stage and grade with smaller size of tumor at diagnosis in new era compared to old era. Conclusion: The new era showed significant changes in the RCC landscape regarding demographic distribution, presentation, and tumor characteristics.