Safety and immunogenicity of a DNA vaccine with subtype C gp120 protein adjuvanted with MF59® or AS01B: a phase 1/2a HIV-1 vaccine trial

Author:

Garrett Nigel12ORCID,Dintwe One34,Monaco Cynthia L.56,Jones Megan3,Seaton Kelly E.7,Church E. Chandler3,Grunenberg Nicole3,Hutter Julia8,deCamp Allan3,Huang Yunda3,Lu Huiyin3,Mann Philipp3,Robinson Samuel T.3,Heptinstall Jack7,Jensen Ryan L.3,Pantaleo Giuseppe9,Ding Song10,Koutsoukos Marguerite11,Hosseinipour Mina C.1213,Van Der Meeren Olivier14,Gilbert Peter B.3,Ferrari Guido7,Andersen-Nissen Erica34,McElrath M. Juliana3,Tomaras Georgia D.7,Gray Glenda E.15,Corey Lawrence3,Kublin James G.3,

Affiliation:

1. Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu–Natal, Durban, South Africa

2. Department of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa

3. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America

4. Cape Town HVTN Immunology Laboratory, Cape Town, South Africa

5. Department of Medicine, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, United States of America

6. Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America

7. Center for Human Systems Immunology and Departments of Surgery, Molecular Genetics and Microbiology, and Immunology, Duke University School of Medicine, Durham, North Carolina, United States of America

8. Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

9. Division of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland

10. EuroVacc Foundation, Lausanne, Switzerland.

11. GlaxoSmithKline, Wavre, Belgium

12. University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

13. UNC Project-Malawi, Lilongwe, Malawi

14. GlaxoSmithKline, Rixensart, Belgium

15. South African Medical Research Council, Tygerberg, South Africa

Funder

Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Bill and Melinda Gates Foundation

Publisher

Ovid Technologies (Wolters Kluwer Health)

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