Use of Modeling and Simulations to Determine Raltegravir Dosing in Neonates: A Model for Safely and Efficiently Determining Appropriate Neonatal Dosing Regimens: IMPAACT P1110

Author:

Clarke Diana F.,Mirochnick Mark,Acosta Edward P.,Capparelli Edmund,Chain Anne,Teppler Hedy,Smith Betsy,Lommerse Jos,

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Pharmacology (medical),Infectious Diseases

Reference16 articles.

1. Raltegravir pharmacokinetics in neonates following maternal dosing;Clarke;J Acquir Immune Defic Syndr.,2014

2. The prenatal and postnatal development of UDP-glucuronyltransferase activity towards bilirubin and the effect of premature birth on this activity in the human liver;Kawade;Biochem J.,1981

3. Ontogeny of hepatic glucuronidation; methods and results;Krekels;Curr Drug Metab.,2012

4. Raltegravir in vitro effect on bilirubin binding;Clarke;Pediatr Infect Dis J.,2013

5. A difference in mortality rate and incidence of kernicterus among premature infants allotted to two prophylactic antibacterial regimens;Andersen;Pediatrics.,1956

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