Dysfunctional natural killer cells, in vivo, are governed by HIV viremia regardless of whether the infected individual is on antiretroviral therapy

Author:

Barker Edward,Martinson Jeff,Brooks Cicely,Landay Alan,Deeks Steven

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference15 articles.

1. Immunologic studies in asymptomatic hemophilia patients. Relationship to acquired immune deficiency syndrome (AIDS);Landay;J Clin Invest,1983

2. Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. I. Defective trigger on NK cells for NKCF production by target cells, and partial restoration by IL 2;Bonavida;J Immunol,1986

3. Alterations in cytotoxic and phenotypic subsets of natural killer cells in acquired immune deficiency syndrome (AIDS);Plaeger-Marshall;J Clin Immunol,1987

4. Spontaneous and interferon resistant natural killer cell anergy in AIDS;Mitchell;AIDS Res,1983

5. Natural killer cell immunodeficiency in HIV disease is manifest by profoundly decreased numbers of CD16+CD56+ cells and expansion of a population of CD16dimCD56− cells with low lytic activity;Hu;J Acquir Immune Defic Syndr Hum Retrovirol,1995

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