First in-human clinical performance of a novel non-cavitating hand-held lensectomy system in 665 consecutive cataract surgeries

Author:

Ianchulev Sean1,Yeu Elizabeth2ORCID,Hu Edward H3,Singh Paul4,Kamthan Gautam1ORCID,Li Gavin1ORCID,Pantanelli Seth5ORCID,Tyson Farrell6

Affiliation:

1. Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.

2. Refractive Surgery, Virginia Eye Consultants, Norfolk, Virginia, USA.

3. Wolfe Eye Clinic, Marshalltown, IA, USA.

4. The Eye Centers of Racine and Kenosha, Racine, Wisconsin.

5. Department of Ophthalmology, Penn State College of Medicine, Hershey, Pennsylvania, USA.

6. The Cape Coral Eye Center (Tyson), Cape Coral, Florida, USA.

Abstract

Purpose: To investigate the intraoperative performance and lens fragmentation efficacy of a non-cavitating handheld lensectomy system in mild, moderate, and severe cataract. Setting: Ambulatory surgical centers Design: Retrospective consecutive case series Methods: 665 consecutive eyes underwent cataract surgery by 12 surgeons using a novel handheld non-cavitating lensectomy system for nuclear fragmentations and extraction. Intraoperative measurements included surgical time, miLOOP pre-treatment, and irrigation fluid use. Results: Of the 665 eyes, 38 (6%), 468 (70%), 126 (19%) and 33 (5%) were Grades 1, 2, 3 and 4 nuclear densities, respectively, as graded by the surgeon intraoperatively. Successful nuclear fragmentation, lens extraction and cortical removal were achieved in all eyes. Total nucleus fragmentation and extraction times were 70.1, 100.3, 132.6 and 287.9 seconds for grades 1,2,3 and 4 respectively (p < 0.001). Additionally, irrigation and aspiration (I/A) cortical removal times were 64.1, 51.1, 48.5 and 59.0 seconds respectively (p = 0.14). There was a low rate of capsular tear (3 cases in 665 surgeries, 0.45%) and no other emergent adverse events (AEs). Conclusion: The miCOR handheld non-cavitating lensectomy system demonstrated nuclear fragmentation and extraction in the absence of intraocular cavitation across all grades of nuclear densities.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Reference13 articles.

1. Cataract and surgery for cataract;Allen;BMJ,2006

2. The evolution of cataract surgery;Davis;Mo Med,2016

3. Cataracts;Liu;Lancet,2017

4. Cataract surgery in developing countries;Khanna;Curr Opin Ophthalmol,2011

5. Microincisions in cataract surgery;Dewey;J Cataract Refract Surg,2014

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3