Pupil size measurements with a multifunctional aberrometer/coherence interferometer/tomographer and two infrared based pupillometers

Abstract

Purpose: To compare precision of pupil size measurements of a multifunctional device (Pentacam AXL Wave (OCULUS; abbreviated as Pentacam) and two infrared based pupillometers (PupilX (Albomed), Colvard (Oasis medical)) and to compare repeatability of Pentacam and PupilX. Setting: Department of Ophthalmology, Goethe-University, Frankfurt, Germany Design: Prospective, comparative trial Methods: Pupil diameter of healthy eyes was measured with Colvard once and Pentacam without (WO) and with glare (WG), PupilX in 0, 1 and 16 lux three times each. In a second series measurements with Pentacam WO and PupilX in 0.06 and 0.12 lux were assessed. Results: 36 eyes of participants aged 21-63 years were included. Mean pupil diameter was 6.05 mm with Colvard, 5.79 mm (1st series), 5.50 mm (2nd series) with Pentacam WO, 3.42 mm WG, 7.26 mm PupilX in 0, 4.67 mm 1, 3.66 mm 16, 6.82 mm in 0.06 and 6.39 mm in 0.12 lux. Measurements with Pentacam WO were significantly different to PupilX in 0, 0.06, 0.12 and 1 lux (all p<0.001), but not to Colvard (p=0.086). Pupil size measured with Pentacam WG and PupilX in 16 lux was not significantly different (p=0.647). Consecutive measurements with Pentacam WO and WG had mean standard deviation of 0.23 and 0.20 mm respectively and with PupilX 0.11 in 0, 0.24 1 and 0.20 mm in 16 lux. Conclusions: Pentacam provided good assessment of pupil size, but was not equivalent to PupilX in low lighting conditions. Repeatability was more favourable for Pentacam.