Cost of improved test and treat strategies in Indonesia

Author:

Hardiawan Donny1,Juwita Mery N.1,Vadra Jorghi1,Prawiranegara Rozar1,Mambea Indra Y.1,Wisaksana Rudi23,Handayani Miasari3,Subronto Yanri W.45,Kusmayanti Nur A.4,Januraga Pande6,Sukmaningrum Evi7,Nurhayati 8,Prameswari Helen D.9,Sulaiman Nurjannah9,Siregar Adiatma Y.M.11011

Affiliation:

1. Center for Economics and Development Studies (CEDS), Department of Economics, Faculty of Economics and Business, Universitas Padjadjaran

2. Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran/Hasan Sadikin Hospital, Bandung

3. Research Centre for Care and Control of Infectious Disease, Universitas Padjadjaran

4. Center for Tropical Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

5. Department of Internal Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada

6. Center for Public Health Innovation, Faculty of Medicine, Udayana University

7. University Center of Excellence – AIDS Research Center Health Policy and Social Innovation, Atma Jaya Catholic University of Indonesia

8. Department of Epidemiology, Faculty of Public Health, Universitas Indonesia

9. Ministry of Health of the Republic of Indonesia

10. Center for Health Technology Assessment (CHTA), Universitas Padjadjaran

11. West Java Development Institute (INJABAR), Universitas Padjadjaran, Indonesia.

Abstract

Objective: To estimate and compare the cost of improved test and treat strategies in Indonesia under HIV Awal (Early) Testing and Treatment Indonesia (HATI) implementation trial in community-based and hospital-based clinics. Design: The cost and outcome [i.e. CD4+ cell count] and viral load (VL) at the beginning of interventions and their change overtime) analysis of Simplifying ART Initiation (SAI), Community-based Organization and community-based ART Service (CBO), Motivational Interviewing (MI), Oral Fluid-based Testing (OFT), and Short Message Service (SMS) reminder in community-based and hospital-based clinics in 2018–2019. Method: We estimated the total and unit costs per patient (under HATI implementation trial interventions) per year from societal perspective in various settings, including costs from patients’ perspective for SAI and MI. We also analyzed the outcome variables (i.e. CD4+ cell count and VL at the beginning of each intervention, the change in CD4+ cell count and VL over time, and adherence rate). Result: The unit cost per patient per year of SAI and SMS were lower at the community-based clinics, and more patients visited community-based clinics. The cost per patient visit from patient perspective for SAI and MI was mostly lower than 10% of the patients’ household monthly expenditure. Average CD4+ cell count was higher and average VL was lower at the start of interventions at the community-based clinics, while average CD4+ cell count and VL changes and adherence rate were similar between the two types of clinics. Conclusion: Community-based clinics hold the potential for scaling up the interventions as it costs less from societal perspective and showed better outcome improvement during the HATI implementation trial.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Immunology,Immunology and Allergy

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