The relationship between alcohol consumption and risk of HIV in married men: a multi-country study on Sub-Saharan Africa

Author:

König Lukas12,Williams Petal Petersen345,Shuper Paul A.678,Probst Charlotte167

Affiliation:

1. Heidelberg Institute of Global Health (HIGH), Medical Faculty and University Hospital, Heidelberg University, Heidelberg, Germany

2. Department of Public Mental Health, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

3. Mental Health, Alcohol, Substance use and Tobacco Research Unit, South African Medical Research Council, Francie Van Zijl Drive, Parow Valley, Cape Town 7501, South Africa

4. Department of Psychiatry and Mental Health, University of Cape Town, J-Block, Groote Schuur Hospital, Observatory, Cape Town, South Africa

5. Department of Global Health, Institute for Life Course Health Research, Stellenbosch University, Stellenbosch, South Africa.

6. Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

7. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada

8. Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

Abstract

Objective: A key factor for incidence of HIV is alcohol consumption. It impacts judgment and the probability to overlook risk-relevant information, which creates a pathway to reduced adherence to biomedical prevention and engagement in condomless sex. We strengthen the understanding of the link between alcohol consumption and risk of HIV among married men in Sub-Saharan Africa (SSA), as we use comprehensive population-level data to provide robust evidence with high external validity. Design: Cross-sectional data analysis Methods: Based on data from Demographic and Health Surveys (DHS) from 20 countries and over 30,000 observations, a minimally and a fully adjusted model with country fixed effects examined the relationship between the men's alcohol consumption (observed by wife) and HIV status (blood test) while accounting for survey weights and controlling for potential confounders. Results: The data comprised a total of 35,108 men. Minimally adjusted (Risk Ratio (RR) 1.25; 95% CI 1.14–1.37; p < 0.001) and fully adjusted (RR 1.26; 95% CI 1.15 - 1.38; p < 0.001) models showed a positive association between the men's alcohol consumption and HIV status. Two sensitivity analyses confirmed the association. Conclusion: In line with previous experimental studies and theoretical framework, this study confirms a risk relationship between alcohol consumption and HIV. Thus, modern HIV/AIDS programs must continue to address the relationship in implementation of prevention and treatment programs.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Immunology,Immunology and Allergy

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