Considerations for long-acting antiretroviral therapy in older persons with HIV-Reference-Cited by-同舟云学术

Considerations for long-acting antiretroviral therapy in older persons with HIV

Published:2023-11-16 Issue:15 Volume:37 Page:2271-2286
ISSN:0269-9370
Container-title:AIDS
language:en
Short-container-title:

Author:

O'Shea Jesse G.¹,Cholli Preetam¹,Heil Emily L.²,Buchacz Kate¹

Affiliation:

1. Division of HIV Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia

2. Department of Practice, Sciences, and Health Outcomes Research, University of Maryland School of Pharmacy, Baltimore, Maryland, USA.

Abstract

People with HIV (PWH) can now enjoy longer, healthier lives due to safe and highly effective antiretroviral therapy (ART), and improved care and prevention strategies. New drug formulations such as long-acting injectables (LAI) may overcome some limitations and issues with oral antiretroviral therapy and strengthen medication adherence. However, challenges and questions remain regarding their use in aging populations. Here, we review unique considerations for LAI-ART for the treatment of HIV in older PWH, including benefits, risks, pharmacological considerations, implementation challenges, knowledge gaps, and identify factors that may facilitate uptake of LA-ART in this population.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Infectious Diseases,Immunology,Immunology and Allergy

Reference89 articles.

1. Global and regional trends of people living with HIV aged 50 and over: Estimates and projections for 2000–2020;Autenrieth;PLoS One,2018

2. Future challenges for clinical care of an ageing population infected with HIV: a modelling study;Smit;Lancet Infect Dis,2015

3. The shifting age distribution of people with HIV using antiretroviral therapy in the United States;Althoff;AIDS,2022

4. HIV and ageing: improving quantity and quality of life;Althoff;Curr Opin HIV AIDS,2016

5. Multimorbidity among persons living with human immunodeficiency virus in the United States;Wong;Clin Infect Dis,2018

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Early Implementation and Outcomes Among People with HIV Who Accessed Long-Acting Injectable Cabotegravir/Rilpivirine at Two Ryan White Clinics in the U.S. South;AIDS Research and Human Retroviruses;2024-07-16

2. Aging on antiretrovirals: reviewing the need for pharmacologic data in elderly people with HIV;AIDS;2024-07-02

3. An update on drug–drug interactions in older adults living with human immunodeficiency virus (HIV);Expert Review of Clinical Pharmacology;2024-06-30

4. Cardiac and Renal Comorbidities in Aging People Living With HIV;Circulation Research;2024-05-24