Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation

Author:

Swaminathan Shriram1,Park In-Ah1,Chacko Bobby12

Affiliation:

1. Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, NSW, Australia.

2. School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.

Abstract

Ureteric encrustation and lithiasis after renal transplantation are rare but not without risk of obstruction and graft loss. Patients are usually asymptomatic, and a majority present with graft dysfunction with imaging demonstrating hydronephrosis and rarely with acute graft pyelonephritis. We compare a case of transplant lithiasis with encrusted pyelitis and highlight key differences in their presentation and workup. A key focus for transplant physicians is to recognize when dealing with transplant hydronephrosis that the presence of a high urine pH and pyuria should be a key indicator to suspect ureteric encrustation to look for a urease-producing organism, recognizing that such organisms require prolonged incubation with urine culturing for up to 72 h.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Transplantation

Reference10 articles.

1. Urolithiasis in renal transplant donors and recipients: an update.;Harraz;Int J Surg,2016

2. Alkaline-encrusted pyelitis/cystitis and urinary tract infection due to Corynebacterium urealyticum: a new severe complication after renal transplantation.;Morales;Transplant Proc,1992

3. Ureteral stenosis after renal transplantation—a single-center 10-year experience.;Gil-Sousa;Transplant Proc,2017

4. Donor and post-transplant ureteroscopy for stone disease in patients with renal transplant: evidence from a systematic review.;Reeves;Curr Opin Urol,2019

5. Contemporary management of renal transplant recipients with de novo urolithiasis: a single institution experience and review of the literature.;Harraz;Exp Clin Transplant,2017

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