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Very important pharmacogene summary: thiopurine S-methyltransferase

  • Published:2010-06 Issue:6 Volume:20 Page:401-405
  • ISSN:1744-6872
  • Container-title:Pharmacogenetics and Genomics
  • language:en
  • Short-container-title:

Author:

Wang Liewei,Pelleymounter Linda,Weinshilboum Richard,Johnson Julie A.,Hebert Joan M.,Altman Russ B.,Klein Teri E.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference46 articles.

1. Metabolism of thiopyrimidines and thiopurines. S-Methylation with S-adenosylmethionine transmethylase and catabolism in mammalian tissues;Remy;J Biol Chem,1963

2. Human kidney thiopurine methyltransferase. Purification and biochemical properties;Woodson;Biochem Pharmacol,1983

3. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity;Weinshilboum;Am J Hum Genet,1980

4. 6-Methylthioguanylic acid, a metabolite of 6-thioguanine;Allan;Biochem Pharmacol,1971

5. Drug methylation in cancer therapy: lessons from the TPMT polymorphism;Krynetski;Oncogene,2003
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