Genetic variation in UGT1A1 typical of Gilbert syndrome is associated with unconjugated hyperbilirubinemia in patients receiving tocilizumab-Reference-Cited by-同舟云学术

Genetic variation in UGT1A1 typical of Gilbert syndrome is associated with unconjugated hyperbilirubinemia in patients receiving tocilizumab

Published:2011-07 Issue:7 Volume:21 Page:365-374
ISSN:1744-6872
Container-title:Pharmacogenetics and Genomics
language:en
Short-container-title:

Author:

Lee Janet S.,Wang Jianmei,Martin Mitchell,Germer Soren,Kenwright Andrew,Benayed Ryma,Spleiss Olivia,Platt Adam,Pilson Robert,Hemmings Andrew,Weinblatt Michael E.,Kaplowitz Neil,Krasnow Joel

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference21 articles.

1. Drug-induced liver injury.;Abboud;Drug Saf,2007

2. Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: the tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study.;Genovese;Arthritis Rheum,2008

3. Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study.;Jones;Ann Rheum Dis,2010

4. Targeting IL-6 in the treatment of inflammatory and autoimmune diseases.;Ding;Expert Opin Investig Drugs,2009

5. Tocilizumab.;Scheinecker;Nat Rev Drug Discov,2009

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4. Diagnosis of gilbert’s syndrome via pyrosequencing in clinical practice;The Russian Archives of Internal Medicine;2019-11-30

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