The impact of pharmacogenetics of metabolic enzymes and transporters on the pharmacokinetics of telmisartan in healthy volunteers

Author:

Yamada Akihiro,Maeda Kazuya,Ishiguro Naoki,Tsuda Yasuhiro,Igarashi Takashi,Ebner Thomas,Roth Willy,Ikushiro Shinichi,Sugiyama Yuichi

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference31 articles.

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2. Pharmacokinetics and safety of intravenous and oral telmisartan 20 and 120 mg in subjects with hepatic impairment compared with healthy volunteers.;Stangier;J Clin Pharmacol,2000

3. Absorption, metabolism, and excretion of intravenously and orally administered 14Ctelmisartan in healthy volunteers.;Stangier;J Clin Pharmacol,2000

4. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1.;Abe;J Biol Chem,1999

5. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters.;Hsiang;J Biol Chem,1999

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