Effect of HNF4α genetic polymorphism G60D on the pharmacokinetics of CYP2D6 substrate tolterodine in healthy Korean individuals-Reference-Cited by-同舟云学术

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Effect of HNF4α genetic polymorphism G60D on the pharmacokinetics of CYP2D6 substrate tolterodine in healthy Korean individuals

Published:2013-03 Issue:3 Volume:23 Page:175-179
ISSN:1744-6872
Container-title:Pharmacogenetics and Genomics
language:en
Short-container-title:

Author:

Jiang Fen,Yeo Chang-Woo,Lee Sang-Seop,Oh Min-Kyung,Ghim Jong-Lyul,Shon Ji-Hong,Kim Ho-Sook,Kim Eun-Young,Kim Dong-Hyun,Shin Jae-Gook

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

Reference7 articles.

1. Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences.;Ryffel;J Mol Endocrinol,2001

2. Genetic polymorphism of hepatocyte nuclear factor-4alpha influences human cytochrome P450 2D6 activity.;Lee;Hepatology,2008

3. Effect of the CYP2D610 genotype on tolterodine pharmacokinetics.;Oishi;Drug Metab Dispos,2010

4. Ketoconazole inhibits the metabolism of tolterodine in subjects with deficient CYP2D6 activity.;Brynne;Br J Clin Pharmacol,1999

5. Effect of gender, sex hormones, time variables and physiological urinary pH on apparent CYP2D6 activity as assessed by metabolic ratios of marker substrates.;Labbe;Pharmacogenetics,2000

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4. Association of Hepatic Nuclear Factor 4 Alpha Gene Polymorphisms With Free Imatinib Plasma Levels and Adverse Reactions in Chinese Gastrointestinal Stromal Tumor Patients;Therapeutic Drug Monitoring;2019-10

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