Cisplatin-induced ototoxicity: a novel approach to an ancient problem-Reference-Cited by-同舟云学术

Cisplatin-induced ototoxicity: a novel approach to an ancient problem

Published:2023-04-10 Issue:5 Volume:33 Page:111-115
ISSN:1744-6872
Container-title:Pharmacogenetics and Genomics
language:en
Short-container-title:

Author:

Omar Nabil E.¹²,Elewa Hazem²

Affiliation:

1. Pharmacy Department, National Center for Cancer Care and Research, Hamad Medical Corporation

2. Clinical and Population Health Research, College of Pharmacy, Qatar University, Doha, Qatar

Abstract

With the scarcity of pharmacological otoprotective agents against cisplatin-induced ototoxicity (CIO), researchers find themselves compelled to look at and navigate all possible strategies to identify ways to prevent CIO. One of these promising strategies is pharmacogenomic implementation. This strategy aims for identifying and detecting high-risk genetic variants to tailor cisplatin therapy to reach the best survival outcomes with the least risk of ototoxicity.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine,General Pharmacology, Toxicology and Pharmaceutics

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